<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL210 IL210b Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ NFV+ 3TC 55

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39A, E40R, T107TA, K122E, D123S, I135L, S162C, K173T, Q174K, D177E, I178L, T200A, Q207E, P243T, V245Q G45GA
>IL210b| codons 38-247
CARMEKEAKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVAVLDVGDAYFSVPLDESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRTKNPELVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQTIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G17X, L19LI, M36I, R41K, L63P, H69K, I93L  
>IL210b| codons 8-99
RPLVSIKVGXQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIPIEIC
GKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005