<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL203 IL203c Israel 2001 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 23
2 AZT+ NFV+ 3TC 54

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    W6WL, T12S, I15V, L19T, M36I, R41K, H69K, L89M I93P
>IL203c| codons 4-99
TLLQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQPGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39E, S48T, V90I, K122E, D123G, I135IT, S162Y, K173A, D177E, T200A, Q207E, V245Q F130FL
>IL203c| codons 38-246
CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTALTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQL

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004