Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL185 | IL185c | Israel | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 13 |
| 2 | 3TC+ NFV+ AZT | 132 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T39E, S48T, K122E, D123G, I135L, A158S, K166R, K173A, D177E, G196K, T200A, Q207E, V245E |
| >IL185c| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP SIFQSSMTRILEPFRAQNPEIVIYQYVDDLYVGSDLEIKQHRAKIEELREHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | T12S, I15V, L19I, E35D, M36I, R41K, K45R, H69K, I85V, L89I, I93L, N98NI |
| >IL185c| codons 9-99 PLVSIKVGGQIKEALLDTGADNTVLEDINLPGKWKPRMIGGIGGFIKVRQYDQILIEICG KKAIGTVLVGPTPVNIVGRNILTQLGCTLIF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |