<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL185 IL185b Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 13
2 3TC+ NFV+ AZT 42

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
>IL185b| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39E, S48T, K122E, D123G, S134SC, A158S, K166R, K173A, D177E, G196K, T200A, Q207E, T216X, V245E S191ST
>IL185b| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPCINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTRILEPFRAQNPEIVIYQYVDDLYVGTDLEIKQHRAKIEELREHLLRWGFTXP
DKKHQKEPPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004