<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL184 IL184a Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ 3TC+ AZT 32
2 D4T+ 3TC+ NFV 7

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, M36I, L38LM, R41K, H69K, T74A, L89M, I93L  
>IL184a| codons 4-99
TLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINMPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39E, I47N, K122E, D123S, E138A, S162C, F171L, K173KEGR, V179VG, T200A, Q207A, R211K, V245Q K220KR, L234LP
>IL184a| codons 38-247
CEEMEKEGKNSKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPLRRQNPDIGIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP
DKRHQKEPPFLWMGYEPHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004