Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL183 | IL183f | Israel | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 5 |
| 2 | NFV+ AZT+ 3TC | 69 |
| 3 | D4T+ 3TC+ NFV | 9 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11I | Q7R, T12S, I15V, L19T, M36I, R41K, L63LP, H69K, T74A, L89M, I93L |
| >IL183f| codons 4-99 TLWRRPLISIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K70KQ | T39E, I47N, K122E, D123S, E138A, A158S, S162C, K173E, T200A, Q207A, R211K, V245Q | S48Y, P95PQ, F116L |
| >IL183f| codons 38-247 CEEMEKEGKNYKIGPENPYNTPVFAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIQHP AGLKKKKSVTVLDVGDAYLSVPLDESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP SIFQCSMTKILEPFREQNPDIVIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |