<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL183 IL183f Israel 2001 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 5
2 NFV+ AZT+ 3TC 69
3 D4T+ 3TC+ NFV 9

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184MV K70KQ     T39E, I47N, K122E, D123S, E138A, A158S, S162C, K173E, T200A, Q207A, R211K, V245Q S48Y, P95PQ, F116L
>IL183f| codons 38-247
CEEMEKEGKNYKIGPENPYNTPVFAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIQHP
AGLKKKKSVTVLDVGDAYLSVPLDESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQCSMTKILEPFREQNPDIVIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I Q7R, T12S, I15V, L19T, M36I, R41K, L63LP, H69K, T74A, L89M, I93L  
>IL183f| codons 4-99
TLWRRPLISIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005