<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL183 IL183e Israel 2001 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 5
2 NFV+ AZT+ 3TC 66

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        T39E, S48T, K122E, D123S, E138A, A158S, S162C, K173E, T200A, Q207A, R211K, V245Q G45R, E79EG, G231V
>IL183e| codons 38-247
CEEMEKERKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRGLNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQCSMTKILEPFREQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP
DKKHQKEPPFLWMVYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    W6WR, T12S, I15V, L19T, K20KR, M36I, R41K, H69K, T74A, L89M I13IK, I93LP
>IL183e| codons 4-99
TLRQRPLVSKKVGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGAVLVGPTPVNIIGRNMLTQPGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005