Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL160 | IL160 | Israel | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 95 |
| 2 | AZT+ 3TC+ DDI | 82 |
| 3 | AZT+ DDI+ SQV | 35 |
| 4 | AZT+ 3TC+ SQV+ NFV | 43 |
| 5 | AZT+ 3TC | 26 |
| 6 | 3TC+ NFV+ AZT | 50 |
| 7 | ABC+ NVP+ D4T | 14 |
| 8 | ABC+ EFV+ D4T | 40 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210LW, T215Y | K103N, G190A | T39E, K43Q, K49R, K101KQ, K102Q, K122E, D123S, I135IT, A158S, S162C, E169A, K173A, Q174K, D177E, T200A, Q207E, R211K, H221HY, V245Q |
| >IL160| codons 38-247 CEELEQEGKISRIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQQNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP SIFQCSMTKILAPFRAKNPEIVIYQYMDDLYVASDLEIGQHRAKIEELREHLWKWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | T12S, I15V, L19I, K20I, M36I, P39PS, R41K, K45R, L63T, H69K, A71IV, I93L |
| >IL160| codons 4-99 TLWQRPLVSIKVGGQIIEALLDTGADNTVLEEINLSGKWKPRMIGGIGGFIKVRQYDQIT IEICGKKVIGTVLVGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |