Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL105 | IL105b | Israel | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 77 |
| 2 | D4T+ DDI+ IDV | 75 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, M184V, T215Y | V60I, K122E, D123E, D177E, I178L, E194EK, G196E, R199*, Q207E, V245T | G152GS, W153R, P225PT |
| >IL105b| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQSRKGSP AIFQSSMTKILEPFRKQNPELVIYQYVDDLYVGSDLKIEQH*TKIEELREHLLRWGFYTP DKKHQKETPFLWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VA | G16E, K20KR, M36I, P39PS, R41K, I64V |
| >IL105b| codons 4-99 TLWQRPLVTIKIEGQLREALLDTGADDTVLEEINLSGKWKPKMIGGIGGFIKVRQYDQIL VEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |