<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL102 IL102a Israel 1999 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 77
2 D4T+ DDI+ NFV 14

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13X, I15V, M36I, L38LF, R41K, H69K, L89M, I93L  
>IL102a| codons 4-99
TLWQRPLVTXKVGGQLKEALLDTGADDTVLEEINFPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V       T39E, K122E, D123S, I135T, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q  
>IL102a| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004