<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL77 IL77a Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NFV 48

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, M36I, N37D, R41K, H69K, L89M, I93L L24L*
>IL77a| codons 4-99
TLWQRPLVTIKIGGQLREAL*DTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  K70KQ     T39E, E40ED, D121DH, K122E, E138A, A158S, S162SC, K166KR, K173A, T200A, Q207G, V245Q  
>IL77a| codons 38-247
CEDMEKEGKISKIGPENPYNTPVFAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQCSMTRILEPFRAQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004