<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL77 IL77a Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NFV 48

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  K70KQ     T39E, E40ED, D121DH, K122E, E138A, A158S, S162SC, K166KR, K173A, T200A, Q207G, V245Q  
>IL77a| codons 38-247
CEDMEKEGKISKIGPENPYNTPVFAIKKKDSTQWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQCSMTRILEPFRAQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, M36I, N37D, R41K, H69K, L89M, I93L L24L*
>IL77a| codons 4-99
TLWQRPLVTIKIGGQLREAL*DTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005