<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL77 IL77b Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NFV 1

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI   G16X, K20R, M36I, N37D, R41K, H69K, L89M, I93L  
>IL77b| codons 4-98
TLWQRPLVTIKIXGQLREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLN

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        T39E, E40ED, G112E, D121DH, K122E, E138EA, A158S, K173A, T200A, Q207G, V245Q D113N
>IL77b| codons 38-247
CEDMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVENAYFSVPLHEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004