Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL49 | IL49 | Israel | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ NFV+ AZT | 8 |
| 2 | 3TC+ D4T+ NFV | 56 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T39E, S48T, K122E, D123N, S134SG, A158S, E169EG, K173A, D177E, T200A, Q207G, R211K, V245Q | N57NH |
| >IL49| codons 38-247 CEEMEKEGKITKIGPENPYHTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPGINNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILGPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88NS, L90LM | Q7QK, L10LI, I15V, G16E, K20RT, E35D, M36I, L38LM, R41RK, R57K, L63T, H69K, T74TS, L89M, I93L |
| >IL49| codons 4-99 TLWKRPIVTIKVEGQLTEALLDTGADDTVLEDINMPGKWKPKMIGGIGGFIKVKQYDQIT IEICGKKAIGSVLVGPTPVNIIGRSMMTQLGCTLNF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |