<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL49 IL49 Israel 2001 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ NFV+ AZT 8
2 3TC+ D4T+ NFV 56

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39E, S48T, K122E, D123N, S134SG, A158S, E169EG, K173A, D177E, T200A, Q207G, R211K, V245Q N57NH
>IL49| codons 38-247
CEEMEKEGKITKIGPENPYHTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPGINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILGPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88NS, L90LM   Q7QK, L10LI, I15V, G16E, K20RT, E35D, M36I, L38LM, R41RK, R57K, L63T, H69K, T74TS, L89M, I93L  
>IL49| codons 4-99
TLWKRPIVTIKVEGQLTEALLDTGADDTVLEDINMPGKWKPKMIGGIGGFIKVKQYDQIT
IEICGKKAIGSVLVGPTPVNIIGRSMMTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005