Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL48 | IL48 | Israel | 1999 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 65 |
| 2 | AZT+ DDC | 39 |
| 3 | DDC+ IDV+ AZT | 136 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, K45R, H69K, L89M, I93L |
| >IL48| codons 4-99 TLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | A98AG | T39E, S48T, K122E, D123G, S162A, K173A, D177E, G196K, T200A, Q207N, R211K, F214FL, V245Q |
| >IL48| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIKQHRAKIEELRNHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |