<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL201 IL201a Israel 1998 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ IDV 16

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, T12S, I15V, L19T, M36I, R41K, L63P, I64L, H69K, K70KE, L89M, I93L  
>IL201a| codons 4-99
TLWQRPIVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
LEICGKEAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     K238KN T39E, K122E, D123S, I135V, I142K, Q145V, A158S, K173A, Q174K, D177E, H198X, T200A, Q207G, R211RK, V245Q  
>IL201a| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSVNNETPGKRYVYNVLPQGWKGSP
SIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQXRAKIEELRGHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDNWTVQPIQLP

References
Author Title Citation
Grossman, Z Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. AAC, 2004