<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL198 IL198c Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ AZT+ IDV 22
2 D4T+ DDI+ IDV 47

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        T39E, S48T, P119PS, K122E, D123S, K126KE, E138A, A158AS, S162C, K173E, T200A, Q207A, R211K, V245Q  
>IL198c| codons 38-247
CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVSLDESFREYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
SIFQCSMTKILEPFREQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    W6L, T12S, I15V, G16R, L19T, M36I, R41K, H69K, T74A, L89M, I93L  
>IL198c| codons 5-99
LLQRPLVSIKVRGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQILI
EICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005