Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL128 | IL128b | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 165 |
| 2 | DDI+ NFV+ AZT | 41 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | K14N, M36I, R41K, H69K, L89M, I93L | A22G |
| >IL128b| codons 4-99 TLWQRPLVTINIGGQLKEGLLDTGADNTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184MV, T215Y | K238KT | T39E, K122E, D123S, I135T, K173T, D177E, T200A, Q207E, V245Q |
| >IL128b| codons 38-247 CEELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRTQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTP DKKHQKEPPFLWMGYELHPDTWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |