Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL128 | IL128e | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 165 |
| 2 | DDI+ NFV+ AZT | 74 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215Y | Y181S | T39E, E44D, V118VI, K122E, D123S, I135T, S163C, K173T, D177E, T200A, Q207E, K223KR, Y232* | W153L, W239R |
| >IL128e| codons 38-244 CEELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGLKGSP AIFQSCMTKILEPFRTQNPEIVISQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTP DKKHQREPPFLWMG*ELHPDKRTVQPI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | K14N, E35D, M36I, R41K, L63LP, H69K, L89M, I93L |
| >IL128e| codons 4-99 TLWQRPLVTINIGGQLKEALLDTGADNTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |