Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL128 | IL128c | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 165 |
| 2 | DDI+ NFV+ AZT | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15IV, E35D, M36I, R41K, L63LP, H69K, L89M, I93L | D29DV |
| >IL128c| codons 4-99 TLWQRPLVTIKVGGQLKEALLDTGAVDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184MV | T215TN | T39E, K122E, D123S, I135T, A158AS, E169EA, K173AT, Q174QK, D177E, T200A, Q207E, V245A |
| >IL128c| codons 38-247 CEELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILAPFRTKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFNTP DKKHQKEPPFLWMGYELHPDKWTVQPIALP |
References
| Author | Title | Citation |
| Grossman, Z | Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir. | AAC, 2004 |