<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IL128 IL128c Israel 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT 165
2 DDI+ NFV+ AZT 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184MV T215TN     T39E, K122E, D123S, I135T, A158AS, E169EA, K173AT, Q174QK, D177E, T200A, Q207E, V245A  
>IL128c| codons 38-247
CEELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILAPFRTKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFNTP
DKKHQKEPPFLWMGYELHPDKWTVQPIALP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15IV, E35D, M36I, R41K, L63LP, H69K, L89M, I93L D29DV
>IL128c| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGAVDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Grossman, Z Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005