Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA17694 | CA41630 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 65 |
| 2 | 3TC+D4T | 22 |
| 3 | 3TC+D4T+IDV | 256 |
| 4 | 3TC+D4T+NFV | 134 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | K20I, L63LP, I64V, K70R, A71AV, V77I, I93IL |
| >CA41630| codons 1-99 PQITLWQRPLVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPVEICGHRVIGTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | A62V, D67G, K219R | V108I | K20R, K43Q, E44D, V106I, T107A, V118I, K122E, Q174E, G196E, H208Y, R211K, K223Q, L228H, E297K, K350E | K102S |
| >CA41631| codons 1-354 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV FVIKKKGSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKSKKSIAILDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKENPDIVI YQYVDDLYVGSDLEIEQHRTKIEELRQYLWKWGFYTPDRKHQQEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLETGKY |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |