<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA17616 CA41473 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+NVP+TDF 19

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, M184MV   Y181C, Y188YH V108VI K20R, V35L, K101R, K122E, I132IL, S162C, K166KR, E203EK, Q207E, R211K, V245E, A272P, E291D, V292I, I293V  
>CA41473| codons 1-300
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTILDVGDAYFSVPL
DEDFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTRILEPFRKQNPDIVI
CQYVDDLHVGSDLEIGQHRTKIKELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K43R, L63P, I72E, V77I  
>CA41472| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWRPKMIGGIGGFIKVRQYD
QIPIEICGHKAEGTVLIGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005