Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14400 | CA41383 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | 353 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62AV | K103N | T27TP, T39TA, E53ED, V90I, K102R, K122KE, T139R, S162SN, D177DE, T200A, R211RK, K281KR, T286TA, A288S, E297K, S322T, Q334L |
| >CA41383| codons 1-356 PISPIETVPVKLKPGMDGPKVKQWPLPEEKIKALVEICAEMEKEGKISKIGPDNPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKSLTEVIPLTKEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYAR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K20KR, A22AV, E35D, N37S, R41K, D60E, L63P |
| >CA41382| codons 1-99 PQITLWQRPLVTIKIGGQLREVLLDTGADDTVLEDMSLPGKWKPKMIGGIGGFIKVRQYE QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |