<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA14400 CA41383 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 353

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62AV K103N   T27TP, T39TA, E53ED, V90I, K102R, K122KE, T139R, S162SN, D177DE, T200A, R211RK, K281KR, T286TA, A288S, E297K, S322T, Q334L  
>CA41383| codons 1-356
PISPIETVPVKLKPGMDGPKVKQWPLPEEKIKALVEICAEMEKEGKISKIGPDNPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKSLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYAR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20KR, A22AV, E35D, N37S, R41K, D60E, L63P  
>CA41382| codons 1-99
PQITLWQRPLVTIKIGGQLREVLLDTGADDTVLEDMSLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005