Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14684 | CA41352 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 70 |
| 2 | AZT+DDI+IDV+NFV+RTV | 61 |
| 3 | None | 13 |
| 4 | APV+D4T+DDI+RTV | 170 |
| 5 | None | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54LV, V82A | L10F, L24I | T12PS, K14KR, I15V, R41RK, L63P, I64V |
| >CA41352| codons 1-99 PQITLWQRPFVSIRVGGQLKEALIDTGADDTVLEEMNLPGKWKPKLIGGIGGFVKVRQYD QIPVEICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KR | V35I, T69TN, K102Q, V106VI, K122E, D123N, I132V, I135T, E169D, F214L |
| >CA41353| codons 1-252 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSITVLDVGDAYFSVPL DENFRKYTAFTVPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSW |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |