Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3984 | CA41337 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NFV | 32 |
| 2 | D4T+EFV+RTV+SQV | 68 |
| 3 | D4T+NVP+RTV+SQV | 181 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N, Y181C | K11KR, E36K, K43E, K122P, D177E, V179VI, T200I, I202V, E203EA, Q207A, R211KQ, I293V, E297A, V317A, I329L, F346Y |
| >CA41337| codons 1-361 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVKICTEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII CQYMDDLYVGSDLEIGQHRIKVAELRAHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGAYYDPSKDLIAELQKQGQGQWTYQIYQEPYKNLKTGKYARMRGA H |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, L90M | G73S | L10I, K20R, E35D, M36I, R41K, D60E, I62V, L63P, A71V, I93L |
| >CA41336| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFLKVRQYE QVPIEICGHKVISTVLVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |