<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA8026 CA41323 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ AZT+ NFV 174
2 DDI+EFV+RTV+SQV 141

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, L74V, M184V   L100I, K103N   E6EK, K46Q, K102KQ, K122E, I135M, S162Y, E169D, G196GE, T200A, Q207K, R211A, V245E, A272P, V292I, I293V  
>CA41323| codons 1-300
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGQISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKQNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILDPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRAKIEELRKHLLAWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTEEAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V, L90M   L10I, K20I, E34EQ, E35DN, M36I, N37S, R41K, D60E, I62V, L63P, I64V, A71V, P79AD, I85IV, I93L  
>CA41322| codons 1-99
PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLQNISLPGKWKPKMIGGIGGFVKVRQYE
QVPVEICGHKVIGTVLVGDTPVNVVGRNLMTQLGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005