Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8026 | CA41323 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 174 |
| 2 | DDI+EFV+RTV+SQV | 141 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L74V, M184V | L100I, K103N | E6EK, K46Q, K102KQ, K122E, I135M, S162Y, E169D, G196GE, T200A, Q207K, R211A, V245E, A272P, V292I, I293V |
| >CA41323| codons 1-300 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGQISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKQNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRAKIEELRKHLLAWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10I, K20I, E34EQ, E35DN, M36I, N37S, R41K, D60E, I62V, L63P, I64V, A71V, P79AD, I85IV, I93L |
| >CA41322| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLQNISLPGKWKPKMIGGIGGFVKVRQYE QVPVEICGHKVIGTVLVGDTPVNVVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |