Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9752 | CA41282 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ 3TC+ D4T | 38 |
| 2 | D4T+NFV+TDF | 73 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L23I, Q58QE | E35D, R41K, L63P, V77I, V82I, I93L |
| >CA41282| codons 1-99 PQITLWQRPLVTIKIGGQLKEAILDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVREYD QIPIEICGHKAIGTVLIGPTPINIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | V21VI, T69S, I135V, K173E, P243S, V245K | N137NH |
| >CA41283| codons 1-252 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSSRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNHETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFREQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQSIKLPEKDSW |
References
| Author | Title | Citation |
| Rhee, SY | Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing. | AAC, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |