Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8352 | CA41261 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+3TC | 121 |
| 2 | D4T+3TC+NVP | 216 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, K70R, Q151M, M184V | D67G, F77FL, F116Y, T215V, K219Q | K103N | K238T | K20R, T39TA, S68G, I135T, I178M, G196E, T200A, Q207E, F214L, L228LH, A272S, K277R, T286A, E297KQ |
| >CA41261| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKRKGGTRWRKLVDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIEQHRAKIEELREHLLRWGLVTPDQKHQKEPPFHWMGYELHPDTWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTEVIPLTQEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, R41K, I62V, I72IV, I93L |
| >CA41260| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QVLIEICGHKAVGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |