Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4307 | CA41254 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 61 |
| 2 | 3TC+D4T+IDV | 35 |
| 3 | DDI+RTV+SQV | 61 |
| 4 | D4T+DDI+RTV+SQV | 44 |
| 5 | 3TC+D4T+IDV+RTV | 13 |
| 6 | 3TC+D4T+IDV+NVP+RTV | 74 |
| 7 | None | 22 |
| 8 | ABC+APV+AZT+DDI+LPV | 52 |
| 9 | 3TC+APV+AZT+DDI+LPV | 31 |
| 10 | 3TC+D4T+LPV+TDF | 61 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I84V | L10IV, I13V, I15V, L19I, K20M, N37NS, L63LP, I64V |
| >CA41254| codons 1-99 PQITLWQRPVVTVKVGGQIMEALLDTGADDTILEEMSLPGRWKPKIVGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, L210W, T215Y | K103KN | V118I, K122E, I178M, T200A, K277R |
| >CA41255| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVIPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |