Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5544 | CA41233 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 113 |
| 2 | 3TC+AZT+IDV | 113 |
| 3 | None | 74 |
| 4 | 3TC+D4T+NVP | 22 |
| 5 | None | 122 |
| 6 | 3TC+D4T+EFV | 58 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T215C | K103N, Y181C | V179E | I135V, I142V, I178M, G196E, F214L, V245N, V261X, A272P, K277R, T286V, E297Q |
| >CA41233| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMEI CQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGLCTPDKKHQKEPPFLWMGYELHPDKWT VQPINLPEKDSWTVNDIQKLXGKLNWASQIYPGIKVRQLCKLLRGVKALTEVIPLTQEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33I | N37S, P39S, L63P, H69Y, A71V, V77I, I93L |
| >CA41232| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMSLSGRWKPKMIGGIGGFIKVRQYD QIPIEICGYKVIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |