Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4773 | CA41231 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | NA |
| 2 | DDI+EFV+NFV | 56 |
| 3 | APV+D4T+EFV+RTV | 212 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69DN, K70R, L74LV, T215F | K219Q | K103N, Y181C, G190A | P9T, K20R, V35VIL, V60VI, A98S, K102Q, V118I, I135T, K166KR, T200A, E203D, H208Y, R211K, F214L, K223Q, L228H, Q242QH |
| >CA41231| codons 1-254 PISPIETVTVKLKPGMDGPRVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKQNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI CQYMDDLYVASDLEIGQHRAKIDELRQYLLKWGLFTPDQKHQQEPPFHWMGYELHPDKWT VHPIVLPEKDSWTV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I54L, I84V, L90M | L33F, Q58E, G73S | L10I, I13V, E35G, M36I, N37D, D60E, Q61E, I62V, L63P, I66V, H69Y, A71V, I72K, P79A |
| >CA41230| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTIFEGIDLPGRWKPKMIGGIGGFLKVREYE EVPIEVCGYKVKSTVLVGATPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |