<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NJIH0200 NJIH0200 Nigeria 2013 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70KR, M184V K219Q K101E, G190A   K20R, V35T, I50IV, V60I, W88C, K104R, K122E, D123N, E138Q, I142V, K166R, K173T, Q174R, D177E, I178M, T200A, Q207E, R211S, F214L  
>NJIH0200| codons 1-238
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKVGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFCEVQLGIPHPAGLEKKRSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNQTPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTRNPEMVI
YQYVDDLYVASDLEIGQHRAKIEELREHLLSWGLTTPDQKHQKEPPFLWMGYELHPDK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, K20I, E35N, M36I, N37D, R41K, R57RK, C67E, H69K, V82I, L89M  
>NJIH0200| codons 3-99
ITLWQRPIVTVRIGGQLIEALLDTGADDTVLENIDLPGKWKPKMIGGIGGFIKVKQYDQI
LIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Chaplin, B Distinct Pattern of Thymidine Analogue Mutations with K65R in Patients Failing Tenofovir-Based Antiretroviral Therapy. ARHR, 2017