Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GV-36 | GV-36.1 | Italy | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | NA |
| 2 | 3TC+D4T+NFV | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32G, Q58E | L10T, Q61QR, L63P, H69K, V77I |
| >GV-36.1| codons 1-99 PQITLWQRPTVTIKIGGQLKEALLDTGADDTGLEEMNLPGRWKPKMIGGIGGFIKVREYD RIPIEICGKKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | S48E, I135T, T165I, T200A, E203EK, Q207E, R211K | N136ND, P150PL |
| >GV-36.1| codons 1-230 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTDNETPGIRYQYNVLLQGWKGSPAIFQSSMIKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDKKHQKEPPFLWM |
References
| Author | Title | Citation |
| Venturi, G | Divergent distribution of HIV-1 drug-resistant variants on and off antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |