<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GV-36 GV-36.1 Italy 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NVP NA
2 3TC+D4T+NFV 71

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V32G, Q58E L10T, Q61QR, L63P, H69K, V77I  
>GV-36.1| codons 1-99
PQITLWQRPTVTIKIGGQLKEALLDTGADDTGLEEMNLPGRWKPKMIGGIGGFIKVREYD
RIPIEICGKKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   S48E, I135T, T165I, T200A, E203EK, Q207E, R211K N136ND, P150PL
>GV-36.1| codons 1-230
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKIEKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTDNETPGIRYQYNVLLQGWKGSPAIFQSSMIKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDKKHQKEPPFLWM

References
Author Title Citation
Venturi, G Divergent distribution of HIV-1 drug-resistant variants on and off antiretroviral therapy. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005