Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GV-32 | GV-32.1 | Italy | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ IDV | 143 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46L, V82A | L63P, A71V, I72V |
| >GV-32.1| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTILEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHKVVGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | R83K, D123E, I195K, T200A |
| >GV-32.1| codons 1-230 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEKGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWM |
References
| Author | Title | Citation |
| Venturi, G | Divergent distribution of HIV-1 drug-resistant variants on and off antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |