Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GV-21 | GV-21.1 | Italy | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC+ SQV | 105 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K20R, T69S, K122E, I135T, K166R, D177DEKN, F214L |
| >GV-21.1| codons 1-230 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPNIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWM |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, N37S, R41K, L63Q, I72V, T74AS |
| >GV-21.1| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QIQIEICGHKAVGAVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Venturi, G | Divergent distribution of HIV-1 drug-resistant variants on and off antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |