Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ML_pt7 | ML128_2 | Italy | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ RTV+ DDI | NA |
| 2 | D4T+DDI+IDV | 26 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, V82A, L90M | K20R, M36I, L63P, C67Y, H69K, A71V, I72V |
| >ML128_2| codons 1-99 PQITLWQRPLVTIKIGGQLREALLDTGADDTILEEINLPGRWKPKIIGGIGGFIKVRQYD QIPIEIYGKKVVGTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215SY | D123E, I178L, R211RK, V245E | K82T |
| >ML128_2| codons 1-254 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNTRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFSTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTV |
References
| Author | Title | Citation |
| Monno, L | Mutational patterns of paired blood and rectal biopsies in HIV-infected patients on HAART. | J Med Virol, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |