<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
VC_pat272 VC272-8 Spain 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215FY   G190A   K49R, R83K, S162ST, R211NS, V245M  
>VC272-8| codons 38-246
CTEMEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQTSMTKILEPFRKQNPDIVIYQYMDDLYVASDLEIGQHRTKIEELRQHLLNWGFFTP
DKKHQKEPPFLWMGYELHPDKWTVQPIML

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88S   K14E, I15V, E35D, N37D, Q61E, L63P, V77I  
>VC272-8| codons 10-97
LVTIEVGGQLKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYDEIPIEICGH
KAIGTVLIGPTPVNIIGRSLLTQIGCTL

References
Author Title Citation
Vidal, C Genotypic and phenotypic resistance patterns in early-stage HIV-1-infected patients failing initial therapy with stavudine, didanosine and nevirapine. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005