<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
VC_pat257 VC257-8 Spain 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215N K103N, Y181C   I47N, R83K, T139TR, R211K, V245VM D237H
>VC257-8| codons 38-246
CTEMEKEGKNSKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFNTP
DKKHQKEPPFLWMGYELHPHKWTVQPIML

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  I50M K20R, Q61QE, L63P, I72V, I93M P39QR
>VC257-8| codons 9-98
PLVTIKIGGQLREALLDTGADDTVLEEMNLQGRWKPKMIGGMGGFIKVRQYDEIPIEICG
HKAVGTVLVGPTPVNIIGRNLLTQMGCTLN

References
Author Title Citation
Vidal, C Genotypic and phenotypic resistance patterns in early-stage HIV-1-infected patients failing initial therapy with stavudine, didanosine and nevirapine. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005