Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| HG034 | HG034 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L19V, L63P, I72M, V77I |
| >HG034| codons 4-99 TLWQRPLVTIKIGGQVKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGHKAMGTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | V108I | T69N, D121H, K122E, I142V, S162C, Q174E, D177E, I178M, E204K, H221HY, K238R |
| >HG034| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTILDVGDAYFSVPLHEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKENPEMVICQYMDDLYVGSDLEIGQHRTKIEKLRQHLLRWGFTTP DKKYQKEPPFLWMGYELHPDRWTVQPIVLP |
References
| Author | Title | Citation |
| Hanna, G | Drug-selected resistance mutations and non-B subtypes in antiretroviral-naive adults with established human immunodeficiency virus infection. | J Infect Dis, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |