Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| HG010 | HG010 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36L, N37S, R41K, L63P |
| >HG010| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K64R, K122E, K173R, D177E, I178M, T200A, Q207A, R211K, V241VI |
| >HG010| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRRQNPEMVIYQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTIQPIVLP |
References
| Author | Title | Citation |
| Hanna, G | Drug-selected resistance mutations and non-B subtypes in antiretroviral-naive adults with established human immunodeficiency virus infection. | J Infect Dis, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |