<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
VL337 VL337 Thailand 1999 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+NNRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, V82A F53L, L89V L10I, I13V, K20I, E35D, M36I, N37D, L63P, H69K, A71V, T74S  
>VL337| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEDIDLPGRWKPKMIVGIGGLIKVRQYD
QIPIEICGKKVIGSVLVGPTPANIIGRNVLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M A62V, V75I, F77L, F116Y     E6D, V8I, K11T, K20R, V35T, T39K, K43E, S68G, D121H, K122E, I135L, I142V, R172K, K173I, Q174K, D177E, I178L, T200A, I202V, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E297K, A304E, E312T  
>VL337| codons 1-324
PISPIDTIPVTLKPGMDGPRVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FVIKRKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL
HEDFRKYTAFTIPSLNNETPGVRYQYNVLPMGWKGSPAIFQSSMTKILEPFKIKNPELVI
YQYMDDLYVGSDLEIGQHRAKVEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTKEAE
LELEENREILKTPVHGVYYDPSKD

References
Author Title Citation
Chantratita, W Prevalence of HIV-1 polymerase gene mutations in pre-treated patients in Thailand. Southeast Asian J Trop Med Public Health, 2002