<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR05 DR05 Cameroon 2012 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+NNRTI+PI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20R, E35N, M36I, N37D, R41K, K43R, R57K, L63P, H69K, K70R, L89M  
>DR05| codons 1-99
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLENIDLPGKWRPKMIGGIGGFIKVKQYD
QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H K20R, V35T, T39K, K43Q, S68G, D121H, K122E, I135T, E169D, K173A, Q174K, D177E, G196E, T200A, Q207A, V245Q, T286A, E291ED, I293IV, E297EK, E312D, G335D  
>DR05| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEQEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPEIVI
YQYVDDLYVGSDLEIEQHRAKIEELRAHLLRWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVPLTKEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQD

References
Author Title Citation
Jenabian, MA Pitfalls of antiretroviral drug resistance genotyping of HIV-1 Group M and Group N from Cameroon by sequenced-based assays. Niger Med J, 2015