Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1141 | CA39292 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 17 |
| 2 | 3TC+AZT+IDV | 27 |
| 3 | 3TC+D4T+DDI | 9 |
| 4 | 3TC+D4T+IDV | 21 |
| 5 | 3TC+DLV+RTV+SQV | 53 |
| 6 | 3TC+D4T+RTV+SQV | 33 |
| 7 | 3TC+D4T+DDI+IDV | 142 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74I, V75T, M184V, L210W, T215Y | K219N | L100I, K103N | V35M, T39A, E40F, K43E, K49KR, V118I, K122KE, D177DE, G196E, R211K, D218E, V245E, A272P, I293V |
| >CA39292| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAFLEEEGKISRIGPENPYNTPV FAIKKKNSDKWRKITDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPENKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48M, I50V, I54V, V82T | G73C | L10I, I15V, K20R, M36I, N37D, I62V, L63P, A71AITV, I72E, I85V |
| >CA39291| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEEIDLPGRWKPKMIMGVGGFVKVRQYD QVPIEICGHKVECTVLVGPTPTNIVGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |