Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA801 | CA39020 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 52 |
| 2 | 3TC+D4T+RTV | 13 |
| 3 | 3TC+D4T+IDV | 54 |
| 4 | D4T+DDI+RTV+SQV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | G73GS | L10I, K20I, K55R, R57K, L63P, A71V |
| >CA39020| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVRVKQYD QIPIEICGHKVISTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | V75A | V35I, K43E, T69TN, V118I, K122E, D123E, I135T, S162Y, Q207E, R211K, E224D, T286A, I293V, E297K | A299AG |
| >CA39021| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEEEGKISKIGPENPYNTPV FAIKKKNSNKWRKLADFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKDPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTKEGE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |