Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16354 | CA38863 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+IDV+NVP | 52 |
| 2 | DDC+EFV+NFV | 174 |
| 3 | 3TC+ABC+RTV | 28 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | D67G, K70T, K219Q | K101P, Y188YC | V60I, S68G, V106VI, K122KE, I135T, D177E, I178M, T200A, R211K, E224D, A272P, K275R, I293V, P294Q, E297K | S191SP |
| >CA38863| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKGGTTWRKVVDFRELNKRTQDFWEVQLGIPHPAGLPKKKSITVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYVDDLCVGPDLEIGQHRAKIEELRQHLLKWGFTTPDQKHQKDPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVQLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, L19I, K20T, E35D, M36L, K43R, I62V, L63P, A71I, T74S, V77I, Q92K, I93L |
| >CA38862| codons 1-99 PQITLWQRPLVTVKIGGQITEALLDTGADDTVLEDLNLPGRWRPKMIGGIGGFIKVRQYD QVPIEICGHKIIGSVLIGPTPVNIIGRNLMTKLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |