Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16276 | CA38705 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 121 |
| 2 | AZT+ 3TC | 69 |
| 3 | D4T+ NFV+ NVP | 82 |
| 4 | DDI+ RTV+ SQV | 47 |
| 5 | APV+ RTV+ ABC+ D4T+ DDI | 148 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219KR | V35I, T39A, E40F, K43E, V60VI, A98S, V118I, K122E, I135T, I142V, R211K, I293V |
| >CA38705| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAFLEEEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I84V, L90M | L10F, L33F, N88D | I13V, I15IV, K45R, L63P, V77VI, P79PH, I93L |
| >CA38704| codons 1-99 PQITLWQRPFVTVKVGGQLKEALLDTGADNTVFEEMNLPGRWKPRMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGHTPVNVIGRDLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |