Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3933 | CA38697 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV+NVP+RTV | 118 |
| 2 | 3TC+AZT+EFV+IDV+RTV | 24 |
| 3 | D4T+IDV+LPV | 35 |
| 4 | AZT+IDV+LPV | 39 |
| 5 | IDV+LPV+TDF | 44 |
| 6 | 3TC+NFV+T20+TDF | 22 |
| 7 | 3TC+NFV+NVP+T20+TDF | 33 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74IV, M184V, L210W, T215Y | L100I, K103N | P4S, T7A, K20R, V35I, K102R, E203K, Q207E, H208Y, R211K, A272G, E297K |
| >CA38697| codons 1-299 PISSIEAVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKRNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIKELREYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYGGIKVKQLCKLLRGTKALTEVIPLTKEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I84V, L90M | G73S | L10I, E35D, M36I, L63P, I64V, A71V |
| >CA38696| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTILEDINLPGRWKPKIIGGIGGFIKVRQYD QIPVEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |