Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA16168 | CA38474 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, I54V, I84V, L90M | N88D | L10Y, I15V, K20R, E35D, M36I, N37NT, K45R, L63P, I64V, A71AT, Q92K, I93L |
| >CA38474| codons 1-99 PQITLWQRPYVTIKVGGQLREALLDTGADNTVLEDITLPGRWKPRMIGGIGGFVKVRQYD QIPVEICGHKTIGTVLVGPTPVNVIGRDLMTKLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K49R, V118VI, K122E, D123S, I135V, A158S, E169D, G196E, T200I, V245M, I293V |
| >CA38475| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRIKIEELRQHLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |